Assessment of the impact of tardive dyskinesia in clinical practice: consensus panel recommendations

May 17, 2022
- Tardive dyskinesia
- Diagnosis and assessment

Tardive dyskinesia (TD) can affect every aspect of patients’ lives, including their social and psychological well-being.¹⁻³ However, patients may find it difficult to discuss the impact of their movement disorder with their healthcare provider.⁴ This is confounded by the lack of measures to assess the functional impact of TD in routine clinical practice.^4,5 Recognizing this gap, a panel of seven experts in psychiatry and movement disorder neurology has developed consensus recommendations for assessing the multi-dimensional impact of TD for patients in routine clinical practice.⁴

Establishing consensus recommendations

The key recommendations were developed following a narrative literature review on the current practices for assessing the impact of TD in clinical settings.⁴ The advisory committee convened to provide comments on the review and answer questions about assessing the impact of TD in clinical practice.⁴ The responses were discussed and then refined at a second meeting, where a general consensus on the recommendations was reached.⁴

Key consensus panel recommendations

The six key consensus recommendations focus on:⁴

1. Diagnosis of TD
2. Assessing the impact of TD
3. The five key domains impacted by TD
4. Time points for assessing TD impact
5. Approaches to assessing the impact of TD
6. Initiating TD treatment

View the infographic that provides a comprehensive summary of each of the consensus panel recommendations listed above

References

McEvoy J, Gandhi SK, Rizio AA, et al. Effect of tardive dyskinesia on quality of life in patients with bipolar disorder, major depressive disorder, and schizophrenia. Qual Life Res 2019;28:3303–3312.
Caroff SN, Yeomans K, Lenderking WR, et al. RE-KINECT: A prospective study of the presence and healthcare burden of tardive dyskinesia in clinical practice settings. J Clin Psychopharmacol 2020;40:259–268.
Ascher-Svanum H, Zhu B, Faries D, et al. Tardive dyskinesia and the 3-year course of schizophrenia: results from a large, prospective, naturalistic study. J Clin Psychiatry 2008;69:1580–1588.
Jackson R, Brams MN, Citrome L, et al. Assessment of the impact of tardive dyskinesia in clinical practice: consensus panel recommendations. Neuropsychiatr Dis Treat 2021;7:1589–1597.
Caroff SN, Ungvari GS, Cunningham Owens DG. Historical perspectives on tardive dyskinesia. J Neurol Sci 2018;389:4–9.

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